CSAD Antibody

Datasheet

Code	CSB-PA006032LA01HU
Size	US$166
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Image	IHC image of CSB-PA006032LA01HU diluted at 1:600 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. IHC image of CSB-PA006032LA01HU diluted at 1:600 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CSAD Polyclonal antibody

Uniprot No.

Q9Y600

Target Names

CSAD

Alternative Names

Csad antibody; CSAD_HUMAN antibody; CSD antibody; Cysteine sulfinic acid decarboxylase antibody; Cysteine-sulfinate decarboxylase antibody; Sulfinoalanine decarboxylase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cysteine sulfinic acid decarboxylase protein (344-493AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CSAD Antibody (Product code: CSB-PA006032LA01HU) is Non-conjugated. For CSAD Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA006032LB01HU	CSAD Antibody, HRP conjugated	ELISA
FITC	CSB-PA006032LC01HU	CSAD Antibody, FITC conjugated
Biotin	CSB-PA006032LD01HU	CSAD Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:500-1:1000

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate.

Gene References into Functions

taurine biosynthesis in vertebrates involves two structurally related PLP-dependent decarboxylases (cysteine sulfinic acid decarboxylase and glutamic acid decarboxylase like 1) PMID: 26327310
The presence of cysteine inhibited ADC, CSAD and GDC activity. PMID: 22718265

Protein Families

Group II decarboxylase family

Tissue Specificity

Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.

Database Links

HGNC: 18966

OMIM: 616569

KEGG: hsa:51380

STRING: 9606.ENSP00000267085

UniGene: Hs.279815

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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