CSMD3 Antibody, Biotin conjugated

Code CSB-PA800102LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CSMD3 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
CSMD3 antibody; KIAA1894CUB and sushi domain-containing protein 3 antibody; CUB and sushi multiple domains protein 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human CUB and sushi domain-containing protein 3 protein (233-380AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in dendrite development.
Gene References into Functions
  1. Nonsynonymous variants of CSMD3 is associated with familial colorectal cancer. PMID: 21351276
  2. CSMD3 encodes a protein with CUB and sushi multiple domains and is a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1 PMID: 12943675
  3. Breakpoints on chromosomes 8 in both patients do not interrupt any known gene but both map in a region containing the CSMD3 gene, which thereby can be considered as a candidate for autistic spectrum disorders PMID: 18270536
  4. Single-nucleotide polymorphisms in CSMD3 is associated with prostate cancer risk in hispanic men. PMID: 19528667
  5. CSMD3 is deleted in a subject with combined tricho-rhino-phalangeal syndrome II with mental retardation and growth hormone deficiency. PMID: 15523607
  6. CSMD3 protein domain structure and the sequence of the cytoplasmic tail are highly conserved between mammals and fish. PMID: 12906867

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
CSMD family
Tissue Specificity
Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis.
Database Links

HGNC: 19291

OMIM: 608399

KEGG: hsa:114788

STRING: 9606.ENSP00000297405

UniGene: Hs.91381

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