CTDNEP1 Antibody

Code CSB-PA05415A0Rb
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA05415A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA05415A0Rb at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CTDNEP1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
CTDNEP1; DULLARD; CTD nuclear envelope phosphatase 1; Serine/threonine-protein phosphatase dullard
Raised in
Species Reactivity
Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA)
Immunogen Species
Homo sapiens (Human)

The CTDNEP1 Antibody (Product code: CSB-PA05415A0Rb) is Non-conjugated. For CTDNEP1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA05415B0Rb CTDNEP1 Antibody, HRP conjugated ELISA
FITC CSB-PA05415C0Rb CTDNEP1 Antibody, FITC conjugated
Biotin CSB-PA05415D0Rb CTDNEP1 Antibody, Biotin conjugated ELISA
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.
Gene References into Functions
  1. CTDNEP1 is upregulated in non-alcoholic fatty liver disease. Up-regulation of miR-122 can trigger the compensatory response of LPIN1 and CTDNEP1 in hepatosteatosis. PMID: 28287811
  2. Dullard participates in a unique phosphatase cascade regulating nuclear membrane biogenesis, a cascade that is conserved from yeast to mammals. PMID: 17420445
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein Families
Dullard family
Tissue Specificity
Muscle specific with lower expression in other metabolic tissues.
Database Links

HGNC: 19085

OMIM: 610684

KEGG: hsa:23399

STRING: 9606.ENSP00000321732

UniGene: Hs.513913

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