CYP26C1 Antibody

Datasheet

Code	CSB-PA751026LA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA751026LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CYP26C1 Polyclonal antibody

Uniprot No.

Q6V0L0

Target Names

CYP26C1

Alternative Names

CP26C_HUMAN antibody; cyp26b1l antibody; CYP26C1 antibody; cyp26d1 antibody; Cytochrome P450 26C1 antibody; Cytochrome P450 family 26 subfamily C polypeptide 1 antibody; Cytochrome P450; subfamily XXVIC polypeptide 1 antibody; EG546726 antibody; FFDD4 antibody; FLJ45301 antibody; MGC158120 antibody; retinoic acid catabolizing enzyme antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytochrome P450 26C1 protein (331-460AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CYP26C1 Antibody (Product code: CSB-PA751026LA01HU) is Non-conjugated. For CYP26C1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA751026LB01HU	CYP26C1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA751026LC01HU	CYP26C1 Antibody, FITC conjugated
Biotin	CSB-PA751026LD01HU	CYP26C1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).

Gene References into Functions

Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency. PMID: 27861128
Elevated expression of CYP26C1 in primary breast carcinomas PMID: 26009309
Focal facial dermal dysplasia, type IV results from the loss of function mutations in CYP26C1. PMID: 23161670
CYP26A1 and CYP26C1 play a pivotal role in the pathogenesis of nonsyndromic bilateral and unilateral optic nerve aplasia. PMID: 21850183
may play a specific role in catabolizing both all-trans and 9-cis isomers of retinoic acid. PMID: 14532297
Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19703508
Observational study of gene-disease association. (HuGE Navigator) PMID: 16933217

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Involvement in disease

Focal facial dermal dysplasia 4 (FFDD4)

Subcellular Location

Membrane; Single-pass membrane protein.

Protein Families

Cytochrome P450 family

Tissue Specificity

Detected in most tissues at very low level.

Database Links

HGNC: 20577

OMIM: 608428

KEGG: hsa:340665

STRING: 9606.ENSP00000285949

UniGene: Hs.369993

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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