CYP26C1 Antibody

Code CSB-PA751026LA01HU
Size US$166
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  • Immunofluorescence staining of HepG2 cells with CSB-PA751026LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYP26C1 Polyclonal antibody
Uniprot No.
Target Names
CYP26C1
Alternative Names
CP26C_HUMAN antibody; cyp26b1l antibody; CYP26C1 antibody; cyp26d1 antibody; Cytochrome P450 26C1 antibody; Cytochrome P450 family 26 subfamily C polypeptide 1 antibody; Cytochrome P450; subfamily XXVIC polypeptide 1 antibody; EG546726 antibody; FFDD4 antibody; FLJ45301 antibody; MGC158120 antibody; retinoic acid catabolizing enzyme antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cytochrome P450 26C1 protein (331-460AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CYP26C1 Antibody (Product code: CSB-PA751026LA01HU) is Non-conjugated. For CYP26C1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA751026LB01HU CYP26C1 Antibody, HRP conjugated ELISA
FITC CSB-PA751026LC01HU CYP26C1 Antibody, FITC conjugated
Biotin CSB-PA751026LD01HU CYP26C1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
Gene References into Functions
  1. Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency. PMID: 27861128
  2. Elevated expression of CYP26C1 in primary breast carcinomas PMID: 26009309
  3. Focal facial dermal dysplasia, type IV results from the loss of function mutations in CYP26C1. PMID: 23161670
  4. CYP26A1 and CYP26C1 play a pivotal role in the pathogenesis of nonsyndromic bilateral and unilateral optic nerve aplasia. PMID: 21850183
  5. may play a specific role in catabolizing both all-trans and 9-cis isomers of retinoic acid. PMID: 14532297
  6. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
  7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19703508
  8. Observational study of gene-disease association. (HuGE Navigator) PMID: 16933217

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Involvement in disease
Focal facial dermal dysplasia 4 (FFDD4)
Subcellular Location
Membrane; Single-pass membrane protein.
Protein Families
Cytochrome P450 family
Tissue Specificity
Detected in most tissues at very low level.
Database Links

HGNC: 20577

OMIM: 608428

KEGG: hsa:340665

STRING: 9606.ENSP00000285949

UniGene: Hs.369993

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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