Cd68 Antibody

Code CSB-PA004951LA01MO
Size US$166
Order now
The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Cd68 Polyclonal antibody
Uniprot No.
Target Names
Cd68
Alternative Names
Cd68 antibody; Macrosialin antibody; CD antigen CD68 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse Macrosialin protein (21-291AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated

The Cd68 Antibody (Product code: CSB-PA004951LA01MO) is Non-conjugated. For Cd68 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA004951LB01MO Cd68 Antibody, HRP conjugated ELISA
FITC CSB-PA004951LC01MO Cd68 Antibody, FITC conjugated
Biotin CSB-PA004951LD01MO Cd68 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Gene References into Functions
  1. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities. PMID: 27869795
  2. Myeloid osteoclast precursors do not express CD68. PMID: 28173622
  3. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver. PMID: 26216124
  4. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age PMID: 25352454
  5. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 / CD68 emigration pathway in macrophages PMID: 22163030
  6. These findings demonstrate a role for CD68 in the function of osteoclasts. PMID: 21991369
  7. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking. PMID: 21572087
  8. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques. PMID: 21339485
  9. Macrosialin does not function as an oxLDL receptor on the cell surface. PMID: 12562841
  10. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice. PMID: 16157452

Show More

Hide All

Subcellular Location
[Isoform Long]: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.; [Isoform Short]: Cell membrane; Single-pass type I membrane protein.
Protein Families
LAMP family
Tissue Specificity
Expressed in tissue macrophages and to a lesser extent in dendritic cells.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*