DDX18 Antibody

Code CSB-PA882116LA01HU
Size US$166
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Image
  • Immunofluorescence staining of Hela cells with CSB-PA882116LA01HU at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DDX18 Polyclonal antibody
Uniprot No.
Target Names
DDX18
Alternative Names
ATP dependent RNA helicase DDX18 antibody; ATP-dependent RNA helicase DDX18 antibody; DDX 18 antibody; DDX18 antibody; DDX18_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 18 antibody; DEAD box polypeptide 18 antibody; DEAD box protein 18 antibody; FLJ33908 antibody; MrDb antibody; Myc regulated DEAD box protein antibody; Myc-regulated DEAD box protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ATP-dependent RNA helicase DDX18 protein (32-110AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DDX18 Antibody (Product code: CSB-PA882116LA01HU) is Non-conjugated. For DDX18 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA882116LB01HU DDX18 Antibody, HRP conjugated ELISA
FITC CSB-PA882116LC01HU DDX18 Antibody, FITC conjugated
Biotin CSB-PA882116LD01HU DDX18 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probable RNA-dependent helicase.
Gene References into Functions
  1. Data show that odulation of RNA helicase DDX18 directly affects growth of tamoxifen-resistant cells, suggesting that it may be a critical downstream effector of the estrogen receptors (ERs) and high mobility group box 2 (HMGB2) complex. PMID: 25284587
  2. We identified 4 nonsynonymous sequence variants of DDX18 in acute myeloid leukemia patient samples PMID: 21653321
  3. findings suggest that MrDb is important for cell proliferation and that its inhibition could prevent tumor cell proliferation. PMID: 18351129
Subcellular Location
Nucleus, nucleolus. Chromosome.
Protein Families
DEAD box helicase family, DDX18/HAS1 subfamily
Database Links

HGNC: 2741

OMIM: 606355

KEGG: hsa:8886

STRING: 9606.ENSP00000263239

UniGene: Hs.744922

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