DDX18 Antibody

Code CSB-PA882116LA01HU
Size US$166
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Image
  • Immunofluorescence staining of Hela cells with CSB-PA882116LA01HU at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DDX18 Polyclonal antibody
Uniprot No.
Target Names
DDX18
Alternative Names
ATP dependent RNA helicase DDX18 antibody; ATP-dependent RNA helicase DDX18 antibody; DDX 18 antibody; DDX18 antibody; DDX18_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 18 antibody; DEAD box polypeptide 18 antibody; DEAD box protein 18 antibody; FLJ33908 antibody; MrDb antibody; Myc regulated DEAD box protein antibody; Myc-regulated DEAD box protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ATP-dependent RNA helicase DDX18 protein (32-110AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DDX18 Antibody (Product code: CSB-PA882116LA01HU) is Non-conjugated. For DDX18 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA882116LB01HU DDX18 Antibody, HRP conjugated ELISA
FITC CSB-PA882116LC01HU DDX18 Antibody, FITC conjugated
Biotin CSB-PA882116LD01HU DDX18 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable RNA-dependent helicase.
Gene References into Functions
  1. Data show that odulation of RNA helicase DDX18 directly affects growth of tamoxifen-resistant cells, suggesting that it may be a critical downstream effector of the estrogen receptors (ERs) and high mobility group box 2 (HMGB2) complex. PMID: 25284587
  2. We identified 4 nonsynonymous sequence variants of DDX18 in acute myeloid leukemia patient samples PMID: 21653321
  3. findings suggest that MrDb is important for cell proliferation and that its inhibition could prevent tumor cell proliferation. PMID: 18351129
Subcellular Location
Nucleus, nucleolus. Chromosome.
Protein Families
DEAD box helicase family, DDX18/HAS1 subfamily
Database Links

HGNC: 2741

OMIM: 606355

KEGG: hsa:8886

STRING: 9606.ENSP00000263239

UniGene: Hs.744922

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