DDX59 Antibody

Code CSB-PA722563LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA722563LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DDX59 Polyclonal antibody
Uniprot No.
Target Names
DDX59
Alternative Names
DDX 59 antibody; DDX59 antibody; DDX59_HUMAN antibody; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 antibody; DEAD box protein 59 antibody; DKFZP564B1023 antibody; OTTHUMP00000033840 antibody; OTTHUMP00000033841 antibody; Probable ATP-dependent RNA helicase DDX59 antibody; RP11-92G12.2 antibody; Zinc finger HIT domain containing protein 5 antibody; Zinc finger HIT domain-containing protein 5 antibody; ZNHIT5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable ATP-dependent RNA helicase DDX59 protein (1-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DDX59 Antibody (Product code: CSB-PA722563LA01HU) is Non-conjugated. For DDX59 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA722563LB01HU DDX59 Antibody, HRP conjugated ELISA
FITC CSB-PA722563LC01HU DDX59 Antibody, FITC conjugated
Biotin CSB-PA722563LD01HU DDX59 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Study presents evidence that DDX59 protein can be upregulated by MEK/ERK/MAP kinase pathway downstream of EGFR and Ras signaling. Increased expression of DDX59 mediates the tumorigenecity of EGFR and Ras in lung cancer. PMID: 29133145
  2. The novel DDX59 mutation is associated with oral-facial-digital syndrome. PMID: 28711741
  3. These data strongly implicate DDX59 RNA helicase family member in the pathogenesis of orofaciodigital syndrome. PMID: 23972372
Involvement in disease
Orofaciodigital syndrome 5 (OFD5)
Subcellular Location
Cytoplasm. Nucleus. Note=Exhibits granular localization in the nucleus, as well as in the cytoplasm.
Protein Families
DEAD box helicase family, DDX59 subfamily
Tissue Specificity
Expressed in fibroblasts (at protein level).
Database Links

HGNC: 25360

OMIM: 174300

KEGG: hsa:83479

STRING: 9606.ENSP00000330460

UniGene: Hs.497332

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