DEUP1 Antibody

Code CSB-PA004729LA01HU
Size US$166
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Image
  • IHC image of CSB-PA004729LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody
Uniprot No.
Target Names
DEUP1
Alternative Names
DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DEUP1 Antibody (Product code: CSB-PA004729LA01HU) is Non-conjugated. For DEUP1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA004729LB01HU DEUP1 Antibody, HRP conjugated ELISA
FITC CSB-PA004729LC01HU DEUP1 Antibody, FITC conjugated
Biotin CSB-PA004729LD01HU DEUP1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
Gene References into Functions
  1. Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
  2. Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
  3. suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074
Subcellular Location
Cytoplasm.
Protein Families
CEP63 family
Database Links

HGNC: 26344

KEGG: hsa:159989

STRING: 9606.ENSP00000298050

UniGene: Hs.436625

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