DEUP1 Antibody

Datasheet

Code	CSB-PA004729LA01HU
Size	US$166
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Image	IHC image of CSB-PA004729LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody

Uniprot No.

Q05D60

Target Names

DEUP1

Alternative Names

DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DEUP1 Antibody (Product code: CSB-PA004729LA01HU) is Non-conjugated. For DEUP1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA004729LB01HU	DEUP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004729LC01HU	DEUP1 Antibody, FITC conjugated
Biotin	CSB-PA004729LD01HU	DEUP1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.

Gene References into Functions

Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074

Subcellular Location

Cytoplasm.

Protein Families

CEP63 family

Database Links

HGNC: 26344

KEGG: hsa:159989

STRING: 9606.ENSP00000298050

UniGene: Hs.436625

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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