DNAH12 Antibody, HRP conjugated

Code CSB-PA747792LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DNAH12 Polyclonal antibody
Uniprot No.
Target Names
DNAH12
Alternative Names
DNAH12 antibody; DHC3 antibody; DLP12 antibody; DNAH12L antibody; DNAH7L antibody; DNAHC3 antibody; DNHD2 antibody; HDHC3 antibody; HL19Dynein heavy chain 12 antibody; axonemal antibody; Axonemal beta dynein heavy chain 12 antibody; Axonemal dynein heavy chain 12-like protein antibody; Axonemal dynein heavy chain 7-like protein antibody; Ciliary dynein heavy chain 12 antibody; Dynein heavy chain 7-like antibody; axonemal antibody; Dynein heavy chain domain-containing protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Dynein heavy chain 12, axonemal protein (2423-2632AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
Gene References into Functions
  1. We show that EGF relocates to the cell centre in a dynein-dependent fashion, concomitant with the sorting away of transferrin receptor, although it remains in Rab5-positive early endosomes. PMID: 17173037
  2. Dynein will initiate translocation of late endosomes to microtubule minus ends only after interacting with betaIII spectrin, which requires the activities of Rab7-RILP and ORP1L. PMID: 17283181
Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme.
Protein Families
Dynein heavy chain family
Database Links

HGNC: 2943

OMIM: 603340

KEGG: hsa:201625

STRING: 9606.ENSP00000312554

UniGene: Hs.201378

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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