DNAH12 Antibody, HRP conjugated

Code CSB-PA747792LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DNAH12 Polyclonal antibody
Uniprot No.
Target Names
DNAH12
Alternative Names
DNAH12 antibody; DHC3 antibody; DLP12 antibody; DNAH12L antibody; DNAH7L antibody; DNAHC3 antibody; DNHD2 antibody; HDHC3 antibody; HL19Dynein heavy chain 12 antibody; axonemal antibody; Axonemal beta dynein heavy chain 12 antibody; Axonemal dynein heavy chain 12-like protein antibody; Axonemal dynein heavy chain 7-like protein antibody; Ciliary dynein heavy chain 12 antibody; Dynein heavy chain 7-like antibody; axonemal antibody; Dynein heavy chain domain-containing protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Dynein heavy chain 12, axonemal protein (2423-2632AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
Gene References into Functions
  1. We show that EGF relocates to the cell centre in a dynein-dependent fashion, concomitant with the sorting away of transferrin receptor, although it remains in Rab5-positive early endosomes. PMID: 17173037
  2. Dynein will initiate translocation of late endosomes to microtubule minus ends only after interacting with betaIII spectrin, which requires the activities of Rab7-RILP and ORP1L. PMID: 17283181
Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme.
Protein Families
Dynein heavy chain family
Database Links

HGNC: 2943

OMIM: 603340

KEGG: hsa:201625

STRING: 9606.ENSP00000312554

UniGene: Hs.201378

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