DNAH3 Antibody

Datasheet

Citations (2)

Code	CSB-PA823461LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA823461LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA823461LA01HU at dilution of 1:100
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DNAH3 Polyclonal antibody

Uniprot No.

Q8TD57

Target Names

DNAH3

Alternative Names

axonemal antibody; Axonemal beta dynein heavy chain 3 antibody; Ciliary dynein heavy chain 3 antibody; Dnah3 antibody; Dnahc3-b antibody; DYH3_HUMAN antibody; Dynein heavy chain 3 antibody; HsADHC3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Dynein heavy chain 3, axonemal protein (1-150AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DNAH3 Antibody (Product code: CSB-PA823461LA01HU) is Non-conjugated. For DNAH3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA823461LB01HU	DNAH3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA823461LC01HU	DNAH3 Antibody, FITC conjugated
Biotin	CSB-PA823461LD01HU	DNAH3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice X Wang, G Shen, Y Yang, C Jiang, T Ruan, X Yang,eLife,2024
Biallelic pathogenic variants in DNAH3 cause male infertility in humans and mice X Wang,Human reproduction open,2024

Customer Reviews and Q&A

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Target Background

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.

Subcellular Location

Cytoplasm, cytoskeleton, cilium axoneme.

Protein Families

Dynein heavy chain family

Tissue Specificity

Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung.

Database Links

HGNC: 2949

OMIM: 603334

KEGG: hsa:55567

STRING: 9606.ENSP00000261383

UniGene: Hs.526500

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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