DNAJB14 Antibody

Datasheet

Code	CSB-PA819454LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA819454LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA819454LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DNAJB14 Polyclonal antibody

Uniprot No.

Q8TBM8

Target Names

DNAJB14

Alternative Names

DNAJB14; UNQ9427/PRO34683; DnaJ homolog subfamily B member 14

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human DnaJ homolog subfamily B member 14 protein (1-244AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DNAJB14 Antibody (Product code: CSB-PA819454LA01HU) is Non-conjugated. For DNAJB14 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA819454LB01HU	DNAJB14 Antibody, HRP conjugated	ELISA
FITC	CSB-PA819454LC01HU	DNAJB14 Antibody, FITC conjugated
Biotin	CSB-PA819454LD01HU	DNAJB14 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70. When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear.; (Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection.

Subcellular Location

Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.

Protein Families

DnaJ family, DNAJB12/DNAJB14 subfamily

Database Links

HGNC: 25881

OMIM: 617487

KEGG: hsa:79982

STRING: 9606.ENSP00000404381

UniGene: Hs.577426

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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