DUSP13 Antibody

Code CSB-PA883436LA01HU
Size US$166
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Image
  • IHC image of CSB-PA883436LA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DUSP13 Polyclonal antibody
Uniprot No.
Target Names
DUSP13
Alternative Names
DUSP13 antibody; DUSP13B antibody; TMDPDual specificity protein phosphatase 13 isoform B antibody; DUSP13B antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Dual specificity phosphatase SKRP4 antibody; Testis- and skeletal-muscle-specific DSP antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Dual specificity protein phosphatase 13 isoform B protein (1-198AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DUSP13 Antibody (Product code: CSB-PA883436LA01HU) is Non-conjugated. For DUSP13 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA883436LB01HU DUSP13 Antibody, HRP conjugated ELISA
FITC CSB-PA883436LC01HU DUSP13 Antibody, FITC conjugated
Biotin CSB-PA883436LD01HU DUSP13 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
Gene References into Functions
  1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
  2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
  3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
Protein Families
Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
Tissue Specificity
Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
Database Links

HGNC: 19681

OMIM: 613191

STRING: 9606.ENSP00000452702

UniGene: Hs.178170

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