DUSP8 Antibody

Datasheet

Code	CSB-PA953662
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA953662(DUSP8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA953662(DUSP8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q13202

Target Names

DUSP8

Alternative Names

C11orf81 antibody; Chromosome 11 open reading frame 81 antibody; Deubiquitinating enzyme 8 antibody; Dual Specificity Phosphatase 8 antibody; Dual specificity phosphatase M3/6 antibody; Dual specificity protein phosphatase 8 antibody; Dual specificity protein phosphatase hVH 5 antibody; Dual specificity protein phosphatase hVH-5 antibody; DUS8 antibody; DUS8_HUMAN antibody; DUSP8 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ42476 antibody; FLJ42958 antibody; H1 phosphatase vaccinia virus homolog antibody; H1 phosphatase; vaccinia virus; homolog of antibody; HB5 antibody; hUBPy antibody; HVH5 antibody; HVH8 antibody; M3/6; mouse; homolog of antibody; Neuronal tyrosine threonine phosphatase 1 antibody; Serine/threonine specific protein phosphatase antibody; Ubiquitin carboxyl terminal hydrolase 8 antibody; Ubiquitin specific processing protease 8 antibody; Ubiquitin thiolesterase 8 antibody; VH5 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human DUSP8

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.

Gene References into Functions

The phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation. PMID: 22100391
DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5 PMID: 13129832
Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5. PMID: 15899389

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily

Tissue Specificity

Abundant in brain, heart and skeletal muscle.

Database Links

HGNC: 3074

OMIM: 602038

KEGG: hsa:1850

STRING: 9606.ENSP00000329539

UniGene: Hs.41688

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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