Disintegrin EC3B Antibody

Code CSB-PA305523HA01EAH
Size US$166
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Product Details

Uniprot No.
Alternative Names
Disintegrin EC3B antibody
Raised in
Rabbit
Species Reactivity
Echis carinatus
Immunogen
Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA)
Immunogen Species
Echis carinatus
Conjugate
Non-conjugated

The Disintegrin EC3B Antibody (Product code: CSB-PA305523HA01EAH) is Non-conjugated. For Disintegrin EC3B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA305523HB01EAH Disintegrin EC3B Antibody, HRP conjugated ELISA
FITC CSB-PA305523HC01EAH Disintegrin EC3B Antibody, FITC conjugated
Biotin CSB-PA305523HD01EAH Disintegrin EC3B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
Subcellular Location
Secreted.
Protein Families
Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily
Tissue Specificity
Expressed by the venom gland.
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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