E2 Antibody, Biotin conjugated

Code CSB-PA361949LD01HMN
Size US$166
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Product Details

Full Product Name
Rabbit anti-Human papillomavirus type 18 E2 Polyclonal antibody
Uniprot No.
Target Names
E2
Alternative Names
E2 antibody; Regulatory protein E2 antibody
Raised in
Rabbit
Species Reactivity
Human papillomavirus type 18
Immunogen
Recombinant Human papillomavirus type 18 Regulatory protein E2 protein (1-365AA)
Immunogen Species
Human papillomavirus type 18
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex.
Subcellular Location
Host nucleus.
Protein Families
Papillomaviridae E2 protein family
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