EIPR1 Antibody

Code CSB-PA681508LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA681508LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA681508LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EIPR1 Polyclonal antibody
Uniprot No.
Target Names
EIPR1
Alternative Names
EIPR1 antibody; TSSC1EARP and GARP complex-interacting protein 1 antibody; Endosome-associated recycling protein-interacting protein antibody; Golgi-associated retrograde protein-interacting protein antibody; Tumor-suppressing STF cDNA 1 protein antibody; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human EARP and GARP complex-interacting protein 1 protein (201-387AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The EIPR1 Antibody (Product code: CSB-PA681508LA01HU) is Non-conjugated. For EIPR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA681508LB01HU EIPR1 Antibody, HRP conjugated ELISA
FITC CSB-PA681508LC01HU EIPR1 Antibody, FITC conjugated
Biotin CSB-PA681508LD01HU EIPR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein(PubMed:27440922). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex. Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles. Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes.
Gene References into Functions
  1. Fluorescence recovery after photobleaching shows that TSSC1 is required for efficient recruitment of GARP to the TGN. These studies thus demonstrate that TSSC1 plays a critical role in endosomal retrieval pathways as a regulator of both GARP and EARP function. PMID: 27440922
  2. TSSC1 inhibits breast cancer cell invasion. Subsequently, TSSC1 is confirmed as a target of Runx2 and is negatively regulated by Runx2. PMID: 23933319
Subcellular Location
Golgi apparatus, trans-Golgi network.
Protein Families
WD repeat EIPR1 family
Database Links

HGNC: 12383

OMIM: 608998

KEGG: hsa:7260

STRING: 9606.ENSP00000371559

UniGene: Hs.502770

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