ELMOD2 Antibody, HRP conjugated

Code CSB-PA815588LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ELMOD2 Polyclonal antibody
Uniprot No.
Target Names
ELMOD2
Alternative Names
9830169G11Rik antibody; ELMD2_HUMAN antibody; ELMO domain containing 2 antibody; ELMO domain containing protein 2 antibody; ELMO domain-containing protein 2 antibody; ELMO/CED 12 domain containing 2 antibody; ELMOD2 antibody; MGC10084 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ELMO domain-containing protein 2 protein (82-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Gene References into Functions
  1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity. PMID: 24616099
  2. TLR3 pathway is dependent on ELMOD2 PMID: 19966137
  3. results suggest ELMOD2 as a novel candidate gene for susceptibility in familial idiopathic pulmonary fibrosis PMID: 16773575
  4. Results describe the purification from bovine testis of an Arl2 GAP and its identity as ELMOD2, a protein with no previously described function. PMID: 17452337
Tissue Specificity
Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophag
Database Links

HGNC: 28111

OMIM: 610196

KEGG: hsa:255520

STRING: 9606.ENSP00000326342

UniGene: Hs.450105

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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