EPPK1 Antibody

Datasheet

Code	CSB-PA007745LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EPPK1 Polyclonal antibody

Uniprot No.

P58107

Target Names

EPPK1

Alternative Names

450 kDa epidermal antigen antibody; Epidermal autoantigen 450K antibody; EPIPL antibody; EPIPL_HUMAN antibody; EPIPL1 antibody; Epiplakin antibody; EPPK1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Epiplakin protein (1-225AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The EPPK1 Antibody (Product code: CSB-PA007745LA01HU) is Non-conjugated. For EPPK1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA007745LB01HU	EPPK1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007745LC01HU	EPPK1 Antibody, FITC conjugated
Biotin	CSB-PA007745LD01HU	EPPK1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture. However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epithelium morphogenesis and integrity. In response to cellular stress, plays a role in keratin filament reorganization, probably by protecting keratin filaments against disruption. During liver and pancreas injuries, plays a protective role by chaperoning disease-induced intermediate filament reorganization.

Gene References into Functions

Epiplakin may be a cytolinker involved in maintaining the integrity of intermediate filaments networks in simple epithelial cells. PMID: 15671067

Subcellular Location

Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. Cell junction, tight junction. Cell projection. Apicolateral cell membrane. Basolateral cell membrane. Cell junction.

Protein Families

Plakin or cytolinker family

Tissue Specificity

Expressed in epithelial cells of liver, small intestine, colon, salivary glands, stomach and appendix.

Database Links

HGNC: 15577

OMIM: 607553

KEGG: hsa:83481

STRING: 9606.ENSP00000436337

UniGene: Hs.200412

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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