EPPK1 Antibody

Code CSB-PA007745LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EPPK1 Polyclonal antibody
Uniprot No.
Target Names
EPPK1
Alternative Names
450 kDa epidermal antigen antibody; Epidermal autoantigen 450K antibody; EPIPL antibody; EPIPL_HUMAN antibody; EPIPL1 antibody; Epiplakin antibody; EPPK1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Epiplakin protein (1-225AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The EPPK1 Antibody (Product code: CSB-PA007745LA01HU) is Non-conjugated. For EPPK1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007745LB01HU EPPK1 Antibody, HRP conjugated ELISA
FITC CSB-PA007745LC01HU EPPK1 Antibody, FITC conjugated
Biotin CSB-PA007745LD01HU EPPK1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture. However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epithelium morphogenesis and integrity. In response to cellular stress, plays a role in keratin filament reorganization, probably by protecting keratin filaments against disruption. During liver and pancreas injuries, plays a protective role by chaperoning disease-induced intermediate filament reorganization.
Gene References into Functions
  1. Epiplakin may be a cytolinker involved in maintaining the integrity of intermediate filaments networks in simple epithelial cells. PMID: 15671067
Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. Cell junction, tight junction. Cell projection. Apicolateral cell membrane. Basolateral cell membrane. Cell junction.
Protein Families
Plakin or cytolinker family
Tissue Specificity
Expressed in epithelial cells of liver, small intestine, colon, salivary glands, stomach and appendix.
Database Links

HGNC: 15577

OMIM: 607553

KEGG: hsa:83481

STRING: 9606.ENSP00000436337

UniGene: Hs.200412

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