ESD Antibody

Code CSB-PA007823LA01HU
Size US$166
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  • Immunofluorescent analysis of U251 cells using CSB-PA007823LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ESD Polyclonal antibody
Uniprot No.
Target Names
ESD
Alternative Names
EC 3.1.2.12 antibody; Es-10 antibody; Es10 antibody; ESD antibody; ESTD_HUMAN antibody; Esterase 10 antibody; Esterase D antibody; Esterase D formylglutathione hydrolase antibody; FGH antibody; FGH, included antibody; FLJ11763 antibody; Methylumbelliferyl acetate deacetylase antibody; MGC139609 antibody; OTTHUMP00000018374 antibody; OTTHUMP00000040929 antibody; S formylglutathione hydrolase antibody; S-formylglutathione hydrolase antibody; S-formylglutathione hydrolase, included antibody; Sid 478 antibody; sid478 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human S-formylglutathione hydrolase protein (2-282AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ESD Antibody (Product code: CSB-PA007823LA01HU) is Non-conjugated. For ESD Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007823LB01HU ESD Antibody, HRP conjugated ELISA
FITC CSB-PA007823LC01HU ESD Antibody, FITC conjugated
Biotin CSB-PA007823LD01HU ESD Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serine hydrolase involved in the detoxification of formaldehyde.
Gene References into Functions
  1. rs7996797 located on chr13q14.1-q14.2 near the ESD gene was the most significantly associated with hallux valgus in females in genome-wide association meta-analyses. PMID: 26337638
  2. Abhydrolase domain-containing protein 11 and Esterase D predict the development of distant metastases and the presence of aggressive lung adenocarcinomas. PMID: 21596165
  3. The analysis involved the data on nine polymorphic codominant loci: HP, GC, TF, PI, PGM1, GLO1, C3, ACP1, and ESD. The loci were selected by significance of differences in genotype frequencies between tuberculosis patients and healthy controls PMID: 12942785
  4. Autoantibodies to EsteD and BB-CK produced in experimental autoimmune uveoretinitis -induced mice were also detected in some endogenous uveitis patients, suggesting that these proteins might be autoantigens. PMID: 18552983
  5. catalytic triad residues--Ser-153, His264, and Asp230--involved in catalysis. Mutagenesis of any of the catalytic triad residues to alanine abolished the enzyme activity. Backbone amides of Leu54 & Met150 are involved in the formation of the oxyanion hole PMID: 19126594

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Subcellular Location
Cytoplasm. Cytoplasmic vesicle.
Protein Families
Esterase D family
Database Links

HGNC: 3465

OMIM: 133280

KEGG: hsa:2098

STRING: 9606.ENSP00000367992

UniGene: Hs.432491

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