ESRP2 Antibody, FITC conjugated

Datasheet

Code	CSB-PA007833LC01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ESRP2 Polyclonal antibody

Uniprot No.

Q9H6T0

Target Names

ESRP2

Alternative Names

Epithelial splicing regulatory protein 2 antibody; ESRP 2 antibody; ESRP2 antibody; ESRP2_HUMAN antibody; FLJ21918 antibody; FLJ22248 antibody; RBM35B antibody; RNA binding motif protein 35A antibody; RNA binding motif protein 35B antibody; RNA binding protein 35B antibody; RNA-binding motif protein 35B antibody; RNA-binding protein 35B antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Epithelial splicing regulatory protein 2 protein (615-720AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gene References into Functions

In conclusion, our findings suggested that IFNG-AS1 may function as an oncogene in pituitary adenoma by interacting with ESRP2. PMID: 30322807
Findings define a direct role for ESRP2 in the generation of conserved repertoires of adult splice isoforms that facilitate terminal differentiation and maturation of hepatocytes. PMID: 26531099
functions of the ESRP2 in an epithelial posttranscriptional gene expression program. PMID: 22354987
ESRP2 coordinates a complex alternative splicing network that adds an important post-transcriptional layer to the changes in gene expression that underlie epithelial-mesenchymal transitions during development and disease. PMID: 20711167

Subcellular Location

Nucleus.

Protein Families

ESRP family

Tissue Specificity

Epithelial cell-specific.

Database Links

HGNC: 26152

OMIM: 612960

KEGG: hsa:80004

STRING: 9606.ENSP00000418748

UniGene: Hs.436585

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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