ETV2 Antibody

Code CSB-PA007855LA01HU
Size US$166
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  • Immunofluorescence staining of HepG2 cells with CSB-PA007855LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ETV2 Polyclonal antibody
Uniprot No.
Target Names
ETV2
Alternative Names
ETV2 antibody; ER71 antibody; ETSRP71ETS translocation variant 2 antibody; Ets-related protein 71 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ETS translocation variant 2 protein (74-201AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ETV2 Antibody (Product code: CSB-PA007855LA01HU) is Non-conjugated. For ETV2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007855LB01HU ETV2 Antibody, HRP conjugated ELISA
FITC CSB-PA007855LC01HU ETV2 Antibody, FITC conjugated
Biotin CSB-PA007855LD01HU ETV2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Gene References into Functions
  1. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. PMID: 28026128
  2. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. PMID: 27488544
  3. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. PMID: 28003219
  4. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. PMID: 25540418
  5. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp PMID: 18270322

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Subcellular Location
Nucleus.
Protein Families
ETS family
Database Links

HGNC: 3491

OMIM: 609358

KEGG: hsa:2116

STRING: 9606.ENSP00000384524

UniGene: Hs.194061

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