ETV2 Antibody, Biotin conjugated

Code CSB-PA007855LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ETV2 Polyclonal antibody
Uniprot No.
Target Names
ETV2
Alternative Names
ETV2 antibody; ER71 antibody; ETSRP71ETS translocation variant 2 antibody; Ets-related protein 71 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human ETS translocation variant 2 protein (74-201AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Gene References into Functions
  1. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. PMID: 28026128
  2. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. PMID: 27488544
  3. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. PMID: 28003219
  4. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. PMID: 25540418
  5. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp PMID: 18270322

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Subcellular Location
Nucleus.
Protein Families
ETS family
Database Links

HGNC: 3491

OMIM: 609358

KEGG: hsa:2116

STRING: 9606.ENSP00000384524

UniGene: Hs.194061

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