FAM3A Antibody

Code CSB-PA064607
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA064607(FAM3A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
FAM3A
Alternative Names
2-19 antibody; 2.19 antibody; Cytokine-like protein 2-19 antibody; DLD antibody; DXS560S antibody; FAM3A antibody; FAM3A_HUMAN antibody; family with sequence similarity 3; member A antibody; Protein FAM3A antibody; XAP 7 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human FAM3A
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a defensin against invading fungal microorganisms.
Gene References into Functions
  1. These results suggest that C/EBPbeta plays an important role in regulating FAM3A promoter activity and FAM3A inhibits adipocyte differentiation. PMID: 27688071
  2. In the present study, we report a putative human homologue of the antimicrobial Drosophila-derived drosomycin, designated drosomycin-like defensin (DLD), with specific antifungal activity. PMID: 18212107
  3. FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism PMID: 24806753
  4. Upregulation of FAM3A by PPARgamma activation is correlated with increased pAkt level in liver cells PMID: 23562554
  5. Expressed prominently in the vascular endothelium, particularly capillaries, also in islets of Langerhans. PMID: 12160727

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Subcellular Location
Secreted.
Protein Families
FAM3 family
Tissue Specificity
In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle and heart.
Database Links

HGNC: 13749

OMIM: 300492

KEGG: hsa:60343

STRING: 9606.ENSP00000352955

UniGene: Hs.289108

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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