FAM49B Antibody

Code CSB-PA873658LA01HU
Size US$166
Order now
The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FAM49B Polyclonal antibody
Uniprot No.
Target Names
FAM49B
Alternative Names
BM 009 antibody; FA49B_HUMAN antibody; Fam49b antibody; Family with sequence similarity 49; member B antibody; L1 antibody; Protein FAM49B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein FAM49B protein (1-324AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FAM49B Antibody (Product code: CSB-PA873658LA01HU) is Non-conjugated. For FAM49B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA873658LB01HU FAM49B Antibody, HRP conjugated ELISA
FITC CSB-PA873658LC01HU FAM49B Antibody, FITC conjugated
Biotin CSB-PA873658LD01HU FAM49B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling. Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization. Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry. Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress.
Gene References into Functions
  1. FAM49B inhibits T cell activation by repressing Rac activity and modulating cytoskeleton reorganization. PMID: 29632189
  2. Three proteins-matrix metalloproteinase-9, neutrophil elastase, and FAM49B-were significantly lower in abundance in samples from women with endometriosis. PMID: 25284053
  3. FAM49B is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
Subcellular Location
Membrane; Lipid-anchor. Mitochondrion.
Protein Families
FAM49 family
Database Links

HGNC: 25216

KEGG: hsa:51571

STRING: 9606.ENSP00000384880

UniGene: Hs.126941

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*