FAR1 Antibody

Code CSB-PA837860LA01HU
Size US$166
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Image
  • IHC image of CSB-PA837860LA01HU diluted at 1:300 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA837860LA01HU diluted at 1:300 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FAR1 Polyclonal antibody
Uniprot No.
Target Names
FAR1
Alternative Names
FAR1; MLSTD2; UNQ2423/PRO4981; Fatty acyl-CoA reductase 1; Male sterility domain-containing protein 2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Fatty acyl-CoA reductase 1 protein (182-343AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The FAR1 Antibody (Product code: CSB-PA837860LA01HU) is Non-conjugated. For FAR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA837860LB01HU FAR1 Antibody, HRP conjugated ELISA
FITC CSB-PA837860LC01HU FAR1 Antibody, FITC conjugated
Biotin CSB-PA837860LD01HU FAR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols. In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
Gene References into Functions
  1. A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. PMID: 25439727
  2. Expression of Far1 increased plasmalogen synthesis in wild-type Chinese hamster ovary cells, strongly suggesting that Far1 is a rate-limiting enzyme for plasmalogen synthesis. PMID: 24108123
  3. ether lipid biosynthesis in mammalian cells is regulated by a negative feedback mechanism that senses cellular plasmalogen levels and appropriately increases or decreases Far1 PMID: 20071337
Involvement in disease
Peroxisomal fatty acyl-CoA reductase 1 disorder (PFCRD)
Subcellular Location
Peroxisome membrane; Single-pass membrane protein.
Protein Families
Fatty acyl-CoA reductase family
Database Links

HGNC: 26222

OMIM: 616107

KEGG: hsa:84188

STRING: 9606.ENSP00000346874

UniGene: Hs.501991

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