FAT3 Antibody

Datasheet

Code	CSB-PA068600
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA068600(FAT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA068600(FAT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

Q8TDW7

Target Names

FAT3

Alternative Names

Cadherin family member 15 antibody; CDHF15 antibody; CDHR10 antibody; FAT tumor suppressor homolog 3 antibody; Fat3 antibody; FAT3_HUMAN antibody; hFat3 antibody; KIAA1989 antibody; Protocadherin Fat 3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human FAT3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

Immunization of rabbits with the synthesized peptide of human FAT3 protein yields the anti-serum, which further undergoes antigen affinity purification to get the FAT3 antibody. This FAT3 antibody is a polyclonal antibody and exists as an unconjugated IgG. It can cross-react with human, mouse, and rat FAT3 protein. Validations of this antibody in ELISA and IHC assays have been tested. The target protein FAT3 plays an important role in axon fasciculation and regulation of the extracellular space surrounding axons during embryonic development.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

May play a role in the interactions between neurites derived from specific subsets of neurons during development.

Gene References into Functions

For Fat3, the Kif5-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 may switch between early and later stages of retinal development. In contrast, P75NTR binding to Kif5B is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale PMID: 27788242

Subcellular Location

Membrane; Single-pass type I membrane protein.

Tissue Specificity

Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate.

Database Links

HGNC: 23112

OMIM: 612483

KEGG: hsa:120114

STRING: 9606.ENSP00000298047

UniGene: Hs.98523

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

The Overview of Hippo Signaling Pathway How do Th1 and Th2 Cells Differentiate? Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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