FOXD1 Antibody

1. as well as stemness abilities but stronger senescence and higher apoptosis rate. CONCLUSION: We found that overexpression of miR-338-5p suppresses glioma cell proliferation, migration, and invasion and accelerates its senescence and apoptosis by decreasing FOXD1 expression via inhibition of activation of MAPK-signaling pathway. PMID: 30225541
2. FOXD1 is overexpressed in osteosarcoma while MiR-30a-5p is lowexpressed. MiR-30a-5p directly regulates FOXD1 by binding its 3'-UTR. PMID: 29936179
3. FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation PMID: 30158529
4. FOXD1 promoted the expression of Plk2 mRNA and protein in colorectal cancer cells. PMID: 29864920
5. Results showed that FOXD1 is a major actor in mammalian reproduction as sequence variants generated recurrent spontaneous abortion (RSA) and embryonic resorption (ER). Data propose that the FOXD1-p.429AlaAla mutation might be used as an RSA molecular marker while FOXD1 p.Ala88Gly variant might have a protective effect. PMID: 27805902
6. our findings define a FOXD1-ALDH1A3 pathway in controling the clonogenic and tumorigenic potential of mesenchymal glioma stem-like cells in glioblastoma tumors PMID: 27569208
7. The role of FOXD1 in glioma tumorigenesis, migration and progression.High FOXD1 expression in glioma. PMID: 28075458
8. FOXD1 promotes breast cancer proliferation and chemotherapeutic drug resistance by targeting p27 PMID: 25462566
9. Lung cancer patients with high FOXD1 expression survive for a significantly shorter time than those with low FOXD1 expression. PMID: 25550559
10. In this review, we focus on the role of four specific FOX factors (FOXD1, FOXL2, FOXO1 and FOXP3) in gonadotropin hormone production PMID: 24099863
11. the level of Smad6s can alter the level of TGF-beta and the subsequent induction of PAI-1 via a FoxD1 transcription site PMID: 15716278

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HGNC: 3802

OMIM: 601091

KEGG: hsa:2297

STRING: 9606.ENSP00000462795

UniGene: Hs.519385