FOXI1 Antibody

Datasheet

Code	CSB-PA008296
Size	US$119
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q12951

Target Names

FOXI1

Alternative Names

FKH10 antibody; FKHL10 antibody; Forkhead (Drosophila) like 10 antibody; Forkhead box I1 antibody; Forkhead box protein I1 antibody; Forkhead like 10 antibody; Forkhead related activator 6 antibody; Forkhead related transcription factor 6 antibody; Forkhead-related protein FKHL10 antibody; Forkhead-related transcription factor 6 antibody; FOXI1 antibody; FOXI1_HUMAN antibody; FREAC 6 antibody; FREAC-6 antibody; FREAC6 antibody; Hepatocyte nuclear factor 3 forkhead homolog 3 antibody; HFH 3 antibody; HFH-3 antibody; HFH3 antibody; HNF 3/fork head homolog 3 antibody; HNF-3 fork-head homolog 3 antibody; HNF-3/fork-head homolog 3 antibody; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds antibody; MGC34197 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human FoxI1.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:5000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.

Gene References into Functions

study reveals that Foxi1/miR-491-5p/Wnt3a/beta-catenin signaling is critical in the progression of GC. Targeting the pathway described in this study may open up new prospects to restrict the progression of gastric cancer PMID: 28358374
We found no evidence for a significant association between mutations of KCNJ10 and FOXI1 with SLC26A4 in Pendred syndrome/enlarged vestibular aqueducts. PMID: 23965030
No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation. PMID: 22412181
SLC26A4, FOXI1 and KCNJ10 are not major determinants in unilateral deafness and enlarged vestibular aqueduct PMID: 20621367
C/EBP alpha and HNF-3 gamma cooperatively regulate CYP3A4 expression in hepatic cells by a mechanism that probably involves chromatin remodeling. PMID: 12695546
Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. PMID: 19214237

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Subcellular Location

Nucleus.

Tissue Specificity

Expressed in kidney.

Database Links

HGNC: 3815

OMIM: 601093

KEGG: hsa:2299

STRING: 9606.ENSP00000304286

UniGene: Hs.87236

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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