FREM1 Antibody

Datasheet
Code CSB-PA686013LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q5H8C1
Image
  • IHC image of CSB-PA686013LA01HU diluted at 1:500 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human FRAS1-related extracellular matrix protein 1 protein (1957-2082AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:500-1:1000
Relevance Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias FRAS1-related extracellular matrix protein 1 (Protein QBRICK), FREM1, C9orf143 C9orf145 C9orf154
Immunogen Species Human
Research Area Developmental Biology
Target Names FREM1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.
Involvement in disease Bifid nose, with or without anorectal and renal anomalies (BNAR); Manitoba oculotrichoanal syndrome (MOTA); Trigonocephaly 2 (TRIGNO2)
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane
Protein Families FRAS1 family
Database Links

HGNC: 23399

OMIM: 248450

KEGG: hsa:158326

STRING: 9606.ENSP00000370262

UniGene: Hs.50850

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