G Antibody

Datasheet

Code	CSB-PA006050GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q8JTH0

Target Names

Alternative Names

G; Glycoprotein

Species Reactivity

Human

Immunogen

Human G-CSF-R

Immunogen Species

Australian bat lyssavirus (isolate Human/AUS/1998) (ABLV)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

Immunization of rabbits with the Australian bat lyssavirus (ABLV) glycoprotein (G) produces the anti-serum, which is purified through antigen affinity to get the anti-ABLV G antibody. This G antibody occurs as an IgG. It can react with human samples. And it is available for use in ELISA analysis. The single fusogenic envelope glycoprotein (G), a key determinant of viral neurotropic and neurovirulent properties, mediates the pH-dependent fusion between ABLV and host cells.

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Target Background

Function

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Subcellular Location

Virion membrane; Single-pass type I membrane protein.

Protein Families

Lyssavirus glycoprotein family

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