GALNT12 Antibody, Biotin conjugated

1. LOH analyses, glycosylation pattern tests and case-control studies, our results did not support the role of c.907G>A, p.(D303N) as a high-penetrance risk allele for polyposis CRC PMID: 29095867
2. Results rule out GALNT12 as a major high familial colorectal cancer susceptibility gene. Additional studies are required to provide further evidence about its role as a moderate/low susceptibility gene in familial aggregation of cancer. PMID: 24115450
3. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes. PMID: 24038392
4. Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. PMID: 22461326
5. cloning and characterization PMID: 12135769
6. The expression of pp-GalNAc-T12 seems to be a negative marker especially of metastatic gastric and colorectal cancer PMID: 15557789
7. inactivating GALNT12 mutations were identified as acquired somatic mutations in a set of 30 microsatellite stable colon tumors. PMID: 19617566

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HGNC: 19877

OMIM: 608812

KEGG: hsa:79695

STRING: 9606.ENSP00000364150

UniGene: Hs.47099