GAREM1 Antibody, HRP conjugated

Code CSB-PA863993LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GAREM1 Polyclonal antibody
Uniprot No.
Target Names
GAREM1
Alternative Names
GAREM1 antibody; C18orf11 antibody; FAM59A antibody; GAREM antibody; GRB2-associated and regulator of MAPK protein 1 antibody; GRB2-associated and regulator of MAPK1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GRB2-associated and regulator of MAPK protein (12-320AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.
Gene References into Functions
  1. We have provided evidence that GAREM1 is involved in the PR interval of ECGs. These findings increase our understanding of the regulatory signals of heart rhythm through intracardiac ganglia of the autonomic nervous system and can be used to guide the development of a therapeutic target for heart conditions, such as atrial fibrillation. PMID: 29273731
  2. suggest that the interplay between 14-3-3, SAM domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells. PMID: 26164232
  3. Data indicate that a subtype of GAREM, GAREM2, is specifically expressed in the mouse, rat, and human brain. PMID: 24003223
  4. Extracellular signal-regulated kinase activation in response to epidermal growth factor stimulation is regulated by the expression of GAREM in COS-7 and HeLa cells. PMID: 19509291
Protein Families
GAREM family
Tissue Specificity
Isoform 1 is ubiquitously expressed.
Database Links

HGNC: 26136

KEGG: hsa:64762

UniGene: Hs.444314

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