GJB5 Antibody

Datasheet

Code	CSB-PA009455DA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA009455DA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA009455DA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GJB5 Polyclonal antibody

Uniprot No.

O95377

Target Names

GJB5

Alternative Names

GJB5; Gap junction beta-5 protein; Connexin-31.1; Cx31.1

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Gap junction beta-5 protein (211-273AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GJB5 Antibody (Product code: CSB-PA009455DA01HU) is Non-conjugated. For GJB5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA009455DB01HU	GJB5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA009455DC01HU	GJB5 Antibody, FITC conjugated
Biotin	CSB-PA009455DD01HU	GJB5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Gene References into Functions

autophagy contributed to Cx31.1 degradation, and clathrin might be involved in the autophagy of Cx31.1. PMID: 25388970
Overexpression of Cx31.1 in H1299 cells reduced cell proliferation, delayed the G1 phase, inhibited anchorage-independent growth, and suppressed cell migration and invasion. Xenografts of Cx31.1 overexpressing H1299 cells had reduced tumourigenicity. PMID: 21777377

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Protein Families

Connexin family, Beta-type (group I) subfamily

Database Links

HGNC: 4287

OMIM: 604493

KEGG: hsa:2709

STRING: 9606.ENSP00000340811

UniGene: Hs.198249

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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