GLYR1 Antibody

Code CSB-PA224597
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA224597(GLYR1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA224597(GLYR1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
GLYR1
Alternative Names
3 hydroxyisobutyrate dehydrogenase like protein antibody; 3-hydroxyisobutyrate dehydrogenase-like protein antibody; BM045 antibody; Cytokine like nuclear factor n pac antibody; Cytokine-like nuclear factor N-PAC antibody; Glyoxylate reductase 1 homolog antibody; GLYR1 antibody; GLYR1_HUMAN antibody; HIBDL antibody; N-PAC antibody; NP60 antibody; Nuclear protein 60 kDa antibody; Nuclear protein NP60 antibody; Nuclear protein of 60 kDa antibody; Putative oxidoreductase GLYR1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human GLYR1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Putative oxidoreductase.
Subcellular Location
Nucleus. Chromosome.
Protein Families
3-hydroxyisobutyrate dehydrogenase family, NP60 subfamily
Database Links

HGNC: 24434

OMIM: 610660

KEGG: hsa:84656

STRING: 9606.ENSP00000322716

UniGene: Hs.387255

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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