GNL2 Antibody

Datasheet

Code	CSB-PA618806LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GNL2 Polyclonal antibody

Uniprot No.

Q13823

Target Names

GNL2

Alternative Names

Autoantigen NGP-1 antibody; Autoantigen NGP1 antibody; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein antibody; FLJ40906 antibody; GNL2 antibody; Guanine nucleotide binding protein-like 2 (nucleolar) antibody; HUMAUANTIG antibody; NGP1 antibody; NOG2_HUMAN antibody; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen antibody; nucleolar G-protein gene 1 antibody; Nucleolar GTP binding protein 2 antibody; Nucleolar GTP-binding protein 2 antibody; Nucleolar GTPase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GNL2 Antibody (Product code: CSB-PA618806LA01HU) is Non-conjugated. For GNL2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA618806LB01HU	GNL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA618806LC01HU	GNL2 Antibody, FITC conjugated
Biotin	CSB-PA618806LD01HU	GNL2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.

Gene References into Functions

NGP-1 promotes cell cycle progression through the activation of the p53/p21(Cip-1/Waf1) pathway. PMID: 26203195
GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells. PMID: 25452588

Subcellular Location

Nucleus, nucleolus.

Protein Families

TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily

Tissue Specificity

Widely expressed, with the highest expression level in testis.

Database Links

HGNC: 29925

OMIM: 609365

KEGG: hsa:29889

STRING: 9606.ENSP00000362153

UniGene: Hs.75528

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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