GPBAR1 Antibody, FITC conjugated

Datasheet
Code CSB-PA819471LC01HU
Size US$299
Uniprot No. Q8TDU6
Protocols ELISA Protocol
Immunogen Recombinant Human G-protein coupled bile acid receptor 1 protein (283-330AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias G-protein coupled bile acid receptor 1 (G-protein coupled receptor GPCR19) (hGPCR19) (Membrane-type receptor for bile acids) (M-BAR) (hBG37) (BG37), GPBAR1, TGR5
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names GPBAR1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Tissue Specificity Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon
Database Links

HGNC: 19680

OMIM: 610147

KEGG: hsa:151306

STRING: 9606.ENSP00000428824

UniGene: Hs.160954

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