GPN3 Antibody

Code CSB-PA009726LA01HU
Size US$166
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Image
  • IHC image of CSB-PA009726LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GPN3 Polyclonal antibody
Uniprot No.
Target Names
GPN3
Alternative Names
ATP-binding domain 1 family member C antibody; ATPBD1C antibody; GPN-loop GTPase 3 antibody; Gpn3 antibody; GPN3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GPN-loop GTPase 3 protein (181-284AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GPN3 Antibody (Product code: CSB-PA009726LA01HU) is Non-conjugated. For GPN3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA009726LB01HU GPN3 Antibody, HRP conjugated ELISA
FITC CSB-PA009726LC01HU GPN3 Antibody, FITC conjugated
Biotin CSB-PA009726LD01HU GPN3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Gene References into Functions
  1. Results indicate that polyubiquitination on lysine 216 is a regulatory process for proteasomal degradation of Gpn3 that is not in a complex with Gpn1, a critical partner of Gpn3 in human cells. PMID: 29029378
  2. Parcs/Gpn3 plays a critical role in the nuclear accumulation of RNAP II, and this function explains the relative importance of Parcs/Gpn3 in cell proliferation. PMID: 21782856
Protein Families
GPN-loop GTPase family
Database Links

HGNC: 30186

KEGG: hsa:51184

STRING: 9606.ENSP00000442770

UniGene: Hs.634680

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