GPX8 Antibody

Datasheet

Code	CSB-PA848417LA01HU
Size	US$166
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Image	Immunofluorescent analysis of Hela cells using CSB-PA848417LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA848417LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA848417LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GPX8 Polyclonal antibody

Uniprot No.

Q8TED1

Target Names

GPX8

Alternative Names

GPX8; UNQ847/PRO1785; Probable glutathione peroxidase 8; GPx-8; GSHPx-8

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable glutathione peroxidase 8 protein (41-209AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GPX8 Antibody (Product code: CSB-PA848417LA01HU) is Non-conjugated. For GPX8 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA848417LB01HU	GPX8 Antibody, HRP conjugated	ELISA
FITC	CSB-PA848417LC01HU	GPX8 Antibody, FITC conjugated
Biotin	CSB-PA848417LD01HU	GPX8 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Study provides evidence that the conserved N-terminal transmembrane domain of GPX8, in addition to its enzymatic activity, is essential for regulating Ca(2+) dynamics revealing a novel level of integration between redox-related proteins and Ca(2+) signaling/homeostasis. PMID: 28129698
GPX8 is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells. PMID: 25557012
Along with the induction of GPX8 in ER-stressed cells, these findings question a ubiquitous role of Ero1alpha as a producer of cytoplasmic ROS under ER stress PMID: 24566470
Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. PMID: 23929719
GPx8 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase PMID: 21215271

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Subcellular Location

Membrane; Single-pass membrane protein.

Protein Families

Glutathione peroxidase family

Database Links

HGNC: 33100

KEGG: hsa:493869

STRING: 9606.ENSP00000423822

UniGene: Hs.289044

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Th17 cell differentiation

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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