Gsta1 Antibody, FITC conjugated

Code CSB-PA009970HC01MO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Gsta1 Polyclonal antibody
Uniprot No.
Target Names
Gsta1
Alternative Names
Gsta1 antibody; Gsta antibody; Gstya antibody; Glutathione S-transferase A1 antibody; EC 2.5.1.18 antibody; 13-hydroperoxyoctadecadienoate peroxidase antibody; EC 1.11.1.- antibody; Androst-5-ene-3,17-dione isomerase antibody; EC 5.3.3.- antibody; GST class-alpha member 1 antibody; Glutathione S-transferase Ya antibody; Glutathione S-transferase Ya1) [Cleaved into: Glutathione S-transferase A1 antibody; N-terminally processed] antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse Glutathione S-transferase A1 protein (2-223AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
Gene References into Functions
  1. GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury. PMID: 27198676
  2. results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT PMID: 24964013
  3. Report increased GSTA1 in airways of asthmatic mice. PMID: 23647087
  4. mitochondrial Gsta1 is induced under oxidative stress PMID: 12020353
  5. Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells PMID: 12557262
  6. This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism. PMID: 16243960
  7. Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs. PMID: 19029078
  8. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis. PMID: 16786188

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Protein Families
GST superfamily, Alpha family
Database Links
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