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HCFC1R1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA865161LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HCFC1R1 Polyclonal antibody
Uniprot No.
Q9NWW0
Target Names
HCFC1R1
Alternative Names
HCF 1 beta propeller interacting protein antibody; HCF-1 beta-propeller-interacting protein antibody; HCF1 beta propeller interacting protein antibody; HCFC1R1 antibody; Host cell factor C1 regulator 1 (XPO1 dependent) antibody; Host cell factor C1 regulator 1 antibody; HPIP antibody; HPIP_HUMAN antibody; Inhibitor of four 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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HCFC1R1 Antibodies

HCFC1R1 Proteins

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Target Background

Function
Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
Gene References into Functions
  1. HPIP overexpression is an independent predictor of platinum-based chemotherapy resistance in epithelial ovarian neoplasms. PMID: 27818289
  2. HPIP promotes thyroid cancer cell growth, migration and epithelial mesenchymal transformation through activating PI3K/AKT signaling pathway. PMID: 26463629
  3. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion PMID: 25800793
  4. HPIP regulates HCF-1 activity by modulating its subcellular localization PMID: 12235138
Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 21198

KEGG: hsa:54985

UniGene: Hs.423103

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