HIST1H2BN Antibody

Datasheet

Code	CSB-PA857877LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human glioma using CSB-PA857877LA01HU at dilution of 1:100 IHC image of CSB-PA857877LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HIST1H2BN Polyclonal antibody

Uniprot No.

Q99877

Target Names

HIST1H2BN

Alternative Names

H2BC15 antibody; H2BFD antibody; HIST1H2BNHistone H2B type 1-N antibody; Histone H2B.d antibody; H2B/d antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Histone H2B type 1-N protein (2-126AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The HIST1H2BN Antibody (Product code: CSB-PA857877LA01HU) is Non-conjugated. For HIST1H2BN Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA857877LB01HU	HIST1H2BN Antibody, HRP conjugated	ELISA
FITC	CSB-PA857877LC01HU	HIST1H2BN Antibody, FITC conjugated
Biotin	CSB-PA857877LD01HU	HIST1H2BN Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:1000

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene References into Functions

Hypomethylation of ATG4A and HIST1H2BN in ovarian tumor-initiating cells predicts a poor prognosis for ovarian cancer patients. PMID: 24256813

Subcellular Location

Nucleus. Chromosome.

Protein Families

Histone H2B family

Database Links

HGNC: 4749

OMIM: 602801

KEGG: hsa:8341

STRING: 9606.ENSP00000380177

UniGene: Hs.534368

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Service

Phage Display Service

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Protein Service

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What Are Histones: Unraveling Their Critical Roles in Disease Pathogenesis Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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