HS3ST1 Antibody

Datasheet

Code	CSB-PA010747LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA010747LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HS3ST1 Polyclonal antibody

Uniprot No.

O14792

Target Names

HS3ST1

Alternative Names

3-OST-1 antibody; 3OST antibody; 3OST1 antibody; EC 2.8.2.23 antibody; h3 OST 1 antibody; h3-OST-1 antibody; Heparan sulfate (glucosamine) 3 O sulfotransferase 1 antibody; Heparan sulfate 3 O sulfotransferase 1 antibody; Heparan sulfate 3-O-sulfotransferase 1 antibody; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1 antibody; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1 antibody; Heparan sulfate glucosamine 3-O-sulfotransferase 1 antibody; Heparin glucosamine 3 O sulfotransferase antibody; HS3S1_HUMAN antibody; HS3ST 1 antibody; Hs3st1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein (21-307AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The HS3ST1 Antibody (Product code: CSB-PA010747LA01HU) is Non-conjugated. For HS3ST1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA010747LB01HU	HS3ST1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA010747LC01HU	HS3ST1 Antibody, FITC conjugated
Biotin	CSB-PA010747LD01HU	HS3ST1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.

Gene References into Functions

Compared with Hs3st1+/+ mice, Hs3st1-/- mice were more susceptible to LPS-induced death due to an increased sensitivity to TNF PMID: 28126521
Golgi-targeted HS3st1 localizes in the Golgi and results in the formation of a single type of AT-binding site and high anti-factor Xa activity PMID: 24247246
In this paper a conformational change is described that occurs in heparan sulfate 3-O-sulfotransferase-1 upon binding to heparan sulfate. PMID: 15096036

Subcellular Location

Golgi apparatus lumen.

Protein Families

Sulfotransferase 1 family

Tissue Specificity

Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.

Database Links

HGNC: 5194

OMIM: 603244

KEGG: hsa:9957

STRING: 9606.ENSP00000002596

UniGene: Hs.507348

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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