Histone H2A Antibody

Datasheet
Code CSB-PA141537
Product Type Polyclonal Antibody
Size US$297
Uniprot No. P0C0S8
Image
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Histone H2A antibody.
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthesized peptide derived from Internal of Human Histone H2A.
Raised in Rabbit
Species Reactivity Human,Mouse
Specificity The antibody detects endogenous levels of total Histone H2A protein.
Tested Applications ELISA,IHC;IHC:1:50-1:100
Relevance Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Albig W., Hum. Genet. 101:284-294(1997).
Albig W., Biol. Chem. 380:7-18(1999).
Dobner T., DNA Seq. 1:409-413(1991).
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias H2A.1b; H2A/c; H2A/d; H2A/i; H2A/n
Immunogen Species Homo sapiens (Human)
Target Names HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular Location Nucleus, Chromosome
Protein Families Histone H2A family
Database Links

HGNC: 4737

OMIM: 602787

KEGG: hsa:8329

STRING: 9606.ENSP00000352627

UniGene: Hs.134999

Related Products

HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3 Antibodies

HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3 Antibodies for Homo sapiens (Human)

HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3 Antibodies for Human

HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3 Proteins

HIST1H2AG/HIST1H2AB/HIST1H2AD/HIST1H2AH/HIST2H2AA3 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.