ICE1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA897466LD01HU
Size US$299
Uniprot No. Q9Y2F5
Protocols ELISA Protocol
Immunogen Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1), ICE1, KIAA0947
Immunogen Species Human
Research Area Others
Target Names ICE1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III
Subcellular Location Nucleus, Nucleus, Cajal body
Protein Families ICE1 family
Database Links

HGNC: 29154

KEGG: hsa:23379

STRING: 9606.ENSP00000296564

UniGene: Hs.449296

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