IGSF10 Antibody

Code CSB-PA111413
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA111413(IGSF10 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
IGSF10
Alternative Names
6530405F15Rik antibody; 9030224D03 antibody; AA409708 antibody; AA536958 antibody; Adlican2 antibody; AI414626 antibody; Calvaria mechanical force protein 608 antibody; CMF608 antibody; IGS10_HUMAN antibody; IgSF10 antibody; Immunoglobulin superfamily member 10 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human IGSF10
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons). May be involved in the maintenance of osteochondroprogenitor cells pool.
Gene References into Functions
  1. These data strongly suggest that mutations in IGSF10 cause delayed puberty in humans, and points to a common genetic basis for conditions of functional hypogonadotropic hypogonadism (HH). PMID: 27137492
Involvement in disease
Mutations in IGSF10 may be a cause of self-limited delayed puberty. This common condition is defined as the absence of testicular enlargement in boys or breast development in girls at an age that is 2-2.5 standard deviations later than the population mean. Self-limited delayed puberty segregates within families, with the majority of families displaying an autosomal dominant pattern of inheritance.
Subcellular Location
Secreted.
Database Links

HGNC: 26384

OMIM: 617351

KEGG: hsa:285313

STRING: 9606.ENSP00000282466

UniGene: Hs.58561

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