IGSF11 Antibody, HRP conjugated

Code CSB-PA691547LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IGSF11 Polyclonal antibody
Uniprot No.
Target Names
IGSF11
Alternative Names
IGSF11 antibody; BTIGSF antibody; CXADRL1 antibody; VSIG3 antibody; Immunoglobulin superfamily member 11 antibody; IgSF11 antibody; Brain and testis-specific immunoglobulin superfamily protein antibody; Bt-IGSF antibody; V-set and immunoglobulin domain-containing protein 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Immunoglobulin superfamily member 11 protein (23-241AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.
Gene References into Functions
  1. Concerted role for IgSF11 and PSD-95 in the regulation of AMPAR-mediated synaptic transmission and plasticity. PMID: 26595655
  2. Molecular cloning of BT-IgSF which is preferentially expressed by brain and testis PMID: 12207903
  3. cell adhesion-inducing function of BT-IgSF suggests a role of the cell surface molecule in the development/function of the central nervous system and spermatogenesis PMID: 15795899
  4. IGSF11 is a good candidate of cancer-testis antigen. Furthermore, suppression of IGSF11 by siRNA retarded the growth of gastric cancer cells. PMID: 16108831
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.
Database Links

HGNC: 16669

OMIM: 608351

KEGG: hsa:152404

STRING: 9606.ENSP00000377370

UniGene: Hs.112873

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