INPP5A Antibody

Datasheet

Code	CSB-PA622780HA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA622780HA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA622780HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA622780HA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) INPP5A Polyclonal antibody

Uniprot No.

Q14642

Target Names

INPP5A

Alternative Names

4 antibody; 43 kDa inositol polyphosphate 5-phophatase antibody; 5-trisphosphate 5-phosphatase antibody; 5PTase antibody; CTCL tumor antigen HD-CL-02 antibody; DKFZp434A1721 antibody; I5P1 antibody; I5P1_HUMAN antibody; Inositol polyphosphate 5 phosphatase antibody; inositol polyphosphate-5-phosphatase A antibody; inositol trisphosphate-5-phosphatase antibody; INPP5A antibody; INPP5A inositol polyphosphate-5-phosphatase antibody; InsP3 5-phosphatase antibody; MGC116947 antibody; MGC116949 antibody; Type I inositol-1 antibody; type I inositol-1,4,5-trisphosphate 5-phophatase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Type I inositol 1,4,5-trisphosphate 5-phosphatase protein (1-409AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The INPP5A Antibody (Product code: CSB-PA622780HA01HU) is Non-conjugated. For INPP5A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA622780HB01HU	INPP5A Antibody, HRP conjugated	ELISA
FITC	CSB-PA622780HC01HU	INPP5A Antibody, FITC conjugated
Biotin	CSB-PA622780HD01HU	INPP5A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.

Gene References into Functions

the overexpression of miR-181a-5p enhanced cell proliferation and invasion and inhibited apoptosis of cervical cancer cells by negatively targeting INPP5A PMID: 28653606
The ataxic phenotype and characteristics neurodegeneration of the Inpp5a Gt(OST50073)Lex mouse indicate a crucial role for Inpp5a in purkinje cells survival. PMID: 26051944
NPP5Amay play a role in development and progression of cutaneous squamous cell carcinoma tumors PMID: 20876729

Subcellular Location

Cell membrane; Lipid-anchor. Cell projection, dendrite.

Protein Families

Inositol 1,4,5-trisphosphate 5-phosphatase type I family

Tissue Specificity

Predominantly expressed in heart, brain, and skeletal muscle. In brain; high level in Purkinje cells.

Database Links

HGNC: 6076

OMIM: 600106

KEGG: hsa:3632

STRING: 9606.ENSP00000357583

UniGene: Hs.523360

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Phosphatidylinositol signaling system

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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