INTS6 Antibody, FITC conjugated

1. DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer. PMID: 25660097
2. Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p. PMID: 25686840
3. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites. PMID: 23986477
4. Findings suggest that EBV encoded miR-BART3* miRNA targets DICE1 tumor suppressor to promote cellular growth and transformation in nasopharyngeal cancer(NPC). PMID: 23280823
5. Molecular characterization of the tumor suppressor gene in lung carcinoma cells PMID: 11939413
6. Somatic mutations were identified in three patients (3/56, 5%), and one novel polymorphism was identified in 3% of ESCC patients (4/136) and 3% of healthy individuals (6/232). We conclude that DICE1 mutations occur in ESCC but are infrequent. PMID: 12527901
7. DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I signaling PMID: 15254679
8. Not mutated in human cancer cell lines which demonstratse 13q14 deletions. PMID: 16271964

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HGNC: 14879

OMIM: 604331

KEGG: hsa:26512

STRING: 9606.ENSP00000310260

UniGene: Hs.439440