IQCG Antibody, Biotin conjugated

Code CSB-PA867116LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IQCG Polyclonal antibody
Uniprot No.
Target Names
IQCG
Alternative Names
IQCG antibody; DRC9Dynein regulatory complex protein 9 antibody; IQ domain-containing protein G antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human IQ domain-containing protein G protein (1-134AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
Gene References into Functions
  1. human NUP98-IQCG fusion protein could induce fatal and transplantable acute myelomonocytic leukemia in a mouse model PMID: 26675333
Subcellular Location
Cytoplasm. Cell projection, cilium, flagellum. Cell projection, cilium. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein Families
DRC9 family
Database Links

HGNC: 25251

OMIM: 612477

KEGG: hsa:84223

STRING: 9606.ENSP00000265239

UniGene: Hs.591675

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