IRF2BP1 Antibody, HRP conjugated

Datasheet
Code CSB-PA815541LB01HU
Size US$299
Uniprot No. Q8IU81
Protocols ELISA Protocol
Immunogen Recombinant Human Interferon regulatory factor 2-binding protein 1 protein (340-499AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1), IRF2BP1
Immunogen Species Homo sapiens (Human)
Research Area Immunology
Target Names IRF2BP1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
Subcellular Location Nucleus
Protein Families IRF2BP family
Database Links

HGNC: 21728

OMIM: 615331

KEGG: hsa:26145

STRING: 9606.ENSP00000307265

UniGene: Hs.515477

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